Sirtuin 1 as a potential therapeutic target in pulmonary artery hypertension
نویسندگان
چکیده
منابع مشابه
Sphingosine kinase 1/sphingosine 1-phosphate signalling pathway as a potential therapeutic target of pulmonary hypertension.
Pulmonary hypertension is characterized by extensive vascular remodelling, leading to increased pulmonary vascular resistance and eventual death due to right heart failure. The pathogenesis of pulmonary hypertension involves vascular endothelial dysfunction and disordered vascular smooth muscle cell (VSMC) proliferation and migration, but the exact processes remain unknown. Sphingosine 1-phosph...
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ژورنال
عنوان ژورنال: Journal of Hypertension
سال: 2018
ISSN: 0263-6352
DOI: 10.1097/hjh.0000000000001694